Structure of PDB 5lvr Chain A

Receptor sequence
>5lvrA (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
DPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTM
SERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSK
IKEAGLID
3D structure
PDB5lvr Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
2.3.1.57: diamine N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 78Y A P747 E756 Y802 N803 Y809 P24 E33 Y79 N80 Y86 MOAD: Kd=250uM
PDBbind-CN: -logKd/Ki=3.60,Kd=250uM
BindingDB: Kd=250000nM
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:5lvr, PDBe:5lvr, PDBj:5lvr
PDBsum5lvr
PubMed27994766
UniProtQ92831|KAT2B_HUMAN Histone acetyltransferase KAT2B (Gene Name=KAT2B)

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