Structure of PDB 5lst Chain A

Receptor sequence
>5lstA (length=617) Species: 9606 (Homo sapiens) [Search protein sequence]
TVLPLYSLGPSGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGIST
LLVLPTGAGKSLCYQLPALLYSRRSPCLTLVVSPLLSLMDDQVSGLPPCL
KAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQLPP
VAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATRRT
ASDVAQHLAVAEEPDAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDS
IIIYCNRREDTERIAALLRTCLHARAPKTTAEAYHAGMCSRERRRVQRAF
MQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQ
PAHCHLFLQPQGEDLRELRRHVHADSTDFLAVKRLVQRVFPACTCTCEQL
SHQAAPGPRRVCMGHERALPIQLTVQALDMPEEAIETLLCYLELHPHHWL
ELLATTYTHCRLNCPGGPAQLQALAHRCPPLAVCLAQQLSVEFDMVKLVD
SMGWELASVRRALCQLQWDHEPRTGVRRGTGVLVEFSELAFHLRSPGDLT
AEEKDQICDFLYGRVQARERQALARLRRTFQAFHSVAFPSCGPCLEQQDE
ERSTRLKDLLGRYFEEE
3D structure
PDB5lst The structural and functional characterization of human RecQ4 reveals insights into its helicase mechanism.
ChainA
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C853 C855 C897 H900 C393 C395 C412 H415
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:5lst, PDBe:5lst, PDBj:5lst
PDBsum5lst
PubMed28653661
UniProtO94761|RECQ4_HUMAN ATP-dependent DNA helicase Q4 (Gene Name=RECQL4)

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