Structure of PDB 5lso Chain A

Receptor sequence
>5lsoA (length=103) Species: 9606 (Homo sapiens) [Search protein sequence]
AMGKCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGA
PDDEAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDL
AEQ
3D structure
PDB5lso Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.
ChainA
Resolution2.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M312 D319 E325 E329 L372 R375 Y376 F377 G378 G379 M15 D22 E28 E32 L75 R78 Y79 F80 G81 G82
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0045292 mRNA cis splicing, via spliceosome

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Molecular Function
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Biological Process
External links
PDB RCSB:5lso, PDBe:5lso, PDBj:5lso
PDBsum5lso
PubMed27753493
UniProtQ96I25|SPF45_HUMAN Splicing factor 45 (Gene Name=RBM17)

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