Structure of PDB 5lrs Chain A

Receptor sequence
>5lrsA (length=236) Species: 1639 (Listeria monocytogenes) [Search protein sequence]
NAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSI
SENGTIMNLQYYKGAFVIMSGFIDTETSVGYYNLEVISEQATAYVIKINE
LKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILT
YVYGKETPDGIKITLDNLTMQELGYSSGIAHSSAVSRIISKLKQEKVIVY
KNSCFYVQNLDYLKRYAPKLDEWFYLACPATWGKLN
3D structure
PDB5lrs Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A M171 S187 S191 K194 M170 S186 S190 K193
BS02 dna A K139 H182 S184 R188 K138 H181 S183 R187
BS03 GSH A Q61 Y62 K64 G65 A66 F67 K122 Q123 Y126 I149 W224 Q60 Y61 K63 G64 A65 F66 K121 Q122 Y125 I148 W223
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5lrs, PDBe:5lrs, PDBj:5lrs
PDBsum5lrs
PubMed27930316
UniProtP22262|PRFA_LISMO Listeriolysin regulatory protein (Gene Name=prfA)

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