Structure of PDB 5lor Chain A

Receptor sequence
>5lorA (length=290) Species: 9606 (Homo sapiens) [Search protein sequence]
VQTMDPEVTLLLQCPGGGLPQEQIQAELSPAHDRRPLPGGDEAITAIWET
RLKAQPWLFDAPKFRLHSATLAPIGSRGPQLLLRLGLTSYRDFLGTNWSS
SAAWLRQQGATDWGDTQAYLADPLGVGAALATADDFLVFLRRSRQVAEAP
GLVDVPGGHPEPQALCPGGSPQHQDLAGQLVVHELFSSVLQEICDEVNLP
LLTLSQPLLLGIARNETSAGRASAEFYVQCSLTSEQVRKHYLSGGPEAHE
STGIFFVETQNVQRLLETEMWAELCPSAKGAIILYNRVQG
3D structure
PDB5lor Structural and functional studies of human NUDT22
ChainA
Resolution2.192 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.45: UDP-sugar diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UPG A L55 F56 K60 Y87 R139 V143 A144 E145 D151 G155 H156 R218 S274 L58 F59 K63 Y90 R142 V146 A147 E148 D154 G158 H159 R221 S277
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008768 UDP-sugar diphosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0052751 GDP-mannose hydrolase activity
Cellular Component
GO:0005654 nucleoplasm

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5lor, PDBe:5lor, PDBj:5lor
PDBsum5lor
PubMed
UniProtQ9BRQ3|NUD22_HUMAN Uridine diphosphate glucose pyrophosphatase NUDT22 (Gene Name=NUDT22)

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