Structure of PDB 5lo9 Chain A

Receptor sequence

>5lo9A (length=471) Species: 765910 (Marichromatium purpuratum 984)

PFERGRTLAEQGDAARGIVACAGCHRADGGGDEALGAARLAGLEPAYLAT
QIERFRAGQRSHPVMSPWAERLTPVDIAAVSAYYGALAPASNARAPSDVD
AAAGRALAETGDWPERDLPACVRCHGPGGVGAGAVFPPLAGQPYSYLLAQ
LQAWGTGRRHGEPMALMGAVAGRLDADEQRALAAYFATRPLARAEAASRF
TPPSRDALPEGPLGEMVRLGARLFRHTNTDPRSAPHVGNDQTCAGCHLDN
GRRADASPMWAAWVAYPAYRGKNQRVDTMAERIQGCFRYSMNAQDSVSGQ
VPETNGLVLDALQSYIFWLATGAPTGDTAMSGRGYPRLQPPAEGFDRTRG
AALYAEHCALCHGAEGEGLLVDGEVVFPPLWGPRSYNWGAGMHRVDTAAA
FIAANMPLLDTVRLTPQEAWDVAAYINAHERPQDPRFDGSVERTAARFHA
SPFDLYGEPLGVDGAVLGQGV

3D structure

• PDB: 5lo9 Electron Accepting Units of the Diheme Cytochrome c TsdA, a Bifunctional Thiosulfate Dehydrogenase/Tetrathionate Reductase.
• Chain: A
• Resolution: 2.75 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEC	A	C21 C24 H25 G36 A37 L40 Y47 R60 H62 V64 M65 W68 V80 Y146 Q150	C21 C24 H25 G36 A37 L40 Y47 R60 H62 V64 M65 W68 V80 Y146 Q150
BS02	HEC	A	Y47 Q51 R54 C121 C124 H125 F136 P137 L139 Y146 W154 R159 E162 M167	Y47 Q51 R54 C121 C124 H125 F136 P137 L139 Y146 W154 R159 E162 M167
BS03	HEC	A	C287 C290 H291 M303 A306 Y310 R326 C330 F331 S334 M335 R377 Y379 Y430	C243 C246 H247 M259 A262 Y266 R282 C286 F287 S290 M291 R333 Y335 Y386
BS04	HEC	A	R123 R269 Q285 A288 G289 C290 H401 C402 C405 H406 F421 P422 L424 Y430 F445 I446 M450 P451	R123 R225 Q241 A244 G245 C246 H357 C358 C361 H362 F377 P378 L380 Y386 F401 I402 M406 P407
BS05	THJ	A	R326 C330 S334	R282 C286 S290

Gene Ontology

Molecular Function

• GO:0009055 electron transfer activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding

External links

• PDB: RCSB:5lo9, PDBe:5lo9, PDBj:5lo9
• PDBsum: 5lo9
• PubMed: 27694441
• UniProt: W0DW89