Structure of PDB 5lhz Chain A

Receptor sequence
>5lhzA (length=78) Species: 9606 (Homo sapiens) [Search protein sequence]
QLLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQT
TRYGENEKLPDYIKQKLQCLSSILLMFS
3D structure
PDB5lhz A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.
ChainA
Resolution2.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q901 V907 V919 Q920 A921 V923 E942 K943 L944 L960 Q16 V22 V34 Q35 A36 V38 E57 K58 L59 L75
External links
PDB RCSB:5lhz, PDBe:5lhz, PDBj:5lhz
PDBsum5lhz
PubMed28202467
UniProtO00444|PLK4_HUMAN Serine/threonine-protein kinase PLK4 (Gene Name=PLK4)

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