Structure of PDB 5lhm Chain A

Receptor sequence
>5lhmA (length=213) Species: 34 (Myxococcus xanthus) [Search protein sequence]
LTQSVLQYIRDSSVRDNDILRDLREETSKLPMQIPPEQGQLLSLLVRLIG
ARKTLEVGVFTGYSTLCTALALPADGRVIACDLSEEWVSIARRYWQRAGV
ADRIEVRLGDAHHSLEALVGSEHRGTFDLAFIDADKESYDFYYEHALRLV
RPGGLIILDNTLWSGKVADPSVVGDPETDSLRRINAKLLTDERVDLSMLP
IADGLTLARKRKL
3D structure
PDB5lhm Functional and structural characterisation of a bacterial O-methyltransferase and factors determining regioselectivity.
ChainA
Resolution1.31 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D142 K145 D168 N169
Catalytic site (residue number reindexed from 1) D133 K136 D159 N160
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A E65 V66 G67 V68 F140 E56 V57 G58 V59 F131
BS02 MG A Q47 D168 A211 G213 Q38 D159 A202 G204
BS03 BU3 A R191 R192 R182 R183
BS04 BU3 A R16 D17 D22 R10 D11 D16
BS05 BU3 A D200 E201 R202 D191 E192 R193
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0032259 methylation

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Molecular Function

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Biological Process
External links
PDB RCSB:5lhm, PDBe:5lhm, PDBj:5lhm
PDBsum5lhm
PubMed27990630
UniProtQ50859

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