Structure of PDB 5lfk Chain A

Receptor sequence
>5lfkA (length=243) Species: 562 (Escherichia coli) [Search protein sequence]
AGPQEFLAAGASFNQVVTALERMMTSQQRLLSDISHELRTPLTRLQLGTA
LLRRRSGESKELERIETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQ
LWSEVLDNAAFEAEQMGKSLTVNFPPGPWPLYGNPNALESALENIVRNAL
RYSHTKIEVGFAVDKDGITITVDDDGPGVSPEDREQIFRPFYRTDEARDR
ESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIWLPLYK
3D structure
PDB5lfk Structural Coupling between Autokinase and Phosphotransferase Reactions in a Bacterial Histidine Kinase.
ChainA
Resolution3.094 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A Y364 V391 R405 T406 A409 T417 G418 L421 L445 Y152 V179 R193 T194 A197 T205 G206 L209 L233
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5lfk, PDBe:5lfk, PDBj:5lfk
PDBsum5lfk
PubMed28552574
UniProtP0AE82|CPXA_ECOLI Sensor histidine kinase CpxA (Gene Name=cpxA)

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