Structure of PDB 5ldm Chain A

Receptor sequence
>5ldmA (length=174) Species: 469008 (Escherichia coli BL21(DE3)) [Search protein sequence]
EPQRLFFAIDLPAEIREQIIHWRAKHFPPEAGRPVAADNLHLTLAFLGEV
SAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYAVTEF
TLYASSFARGRTRYTPLKRWALTQ
3D structure
PDB5ldm Structural aspects of nucleotide ligand binding by a bacterial 2H phosphoesterase.
ChainA
Resolution2.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.58: RNA 2',3'-cyclic 3'-phosphodiesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2AM A F8 H43 T45 F48 H125 T127 R130 F6 H41 T43 F46 H123 T125 R128 MOAD: Ka=7210M^-1
PDBbind-CN: -logKd/Ki=3.86,Kd=139uM
Gene Ontology
Molecular Function
GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
GO:0005524 ATP binding
GO:0008081 phosphoric diester hydrolase activity
GO:0008664 RNA 2',3'-cyclic 3'-phosphodiesterase activity
GO:0016787 hydrolase activity
GO:0016874 ligase activity

View graph for
Molecular Function
External links
PDB RCSB:5ldm, PDBe:5ldm, PDBj:5ldm
PDBsum5ldm
PubMed28141848
UniProtA0A140NFI1

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