Structure of PDB 5ldg Chain A

Receptor sequence
>5ldgA (length=310) Species: 34256 (Mentha x piperita) [Search protein sequence]
QRYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELN
VSENRLVFHQLDVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGD
VSVFNEYIEADFKALQALEAGAKEEPPFKPKANGEMIEKFEGAKDCVVTN
YYGPKRLTQALIPLLQLSPSPRIVNVSSSFGSLLLLWNEWAKGVLGDEDR
LTEERVDEVVEVFLKDIKEGKLEESQWPPHFAAERVSKAALNAYTKIAAK
KYPSFRINAICPGYAKTDITFHAGPLSVAEAAQVPVKLALLPDGGPSGCF
FPRDKALALY
3D structure
PDB5ldg Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases.
ChainA
Resolution1.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.1.82: (-)-isopiperitenone reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A G12 N14 K15 G16 I17 R37 R41 D66 V67 N93 A94 G95 V96 V180 K242 P266 G267 Y268 A269 T271 I273 T274 G8 N10 K11 G12 I13 R33 R37 D62 V63 N89 A90 G91 V92 V176 K238 P262 G263 Y264 A265 T267 I269 T270
BS02 IT9 A S97 S182 F184 F235 E238 S93 S178 F180 F231 E234
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0052581 (-)-isopiperitenone reductase activity
GO:0070402 NADPH binding
Biological Process
GO:0006720 isoprenoid metabolic process
GO:0016114 terpenoid biosynthetic process
GO:0031525 menthol biosynthetic process
GO:0042214 terpene metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ldg, PDBe:5ldg, PDBj:5ldg
PDBsum5ldg
PubMed27411040
UniProtQ6WAU1|IPIPR_MENPI (-)-isopiperitenone reductase

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