Structure of PDB 5lak Chain A

Receptor sequence
>5lakA (length=303) Species: 1041929 (Cavally virus) [Search protein sequence]
SAASNPSISHIVLEMPVAINPLIKYTTRTSVSSLRGAVVNGYIYIQRHLF
GSKKQEFEACYNNGKGLLNCKNLERSKYDIDSAELIGTLIRIPLHDKHSI
PHISIHPDPLSYNGPVTLYLSRYDTNKDVLCVHTGFMSEGHHDIKTVFGD
CGGMLFDPKGRLLGLHCAGSDDVVFMDTTTGKSNIWTSYKLQHPSEIMIT
LNNEINLPNPANYDFETTKVVYQHPLRNVCATLETLQHLTNKTNAKLPYD
SRLLSDFNITAEQYNQYGYYIDYNNFVNNFNRYTTTTIGTKSFETCIKYG
LMD
3D structure
PDB5lak Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus.
ChainA
Resolution2.299 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S52 T148 F150 G151 C153 H168 A170 G171 S172 D173 Y215 D216 E218 T220 S52 T146 F148 G149 C151 H166 A168 G169 S170 D171 Y213 D214 E216 T218
BS02 peptide A R28 T29 R28 T29
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:5lak, PDBe:5lak, PDBj:5lak
PDBsum5lak
PubMed31078932
UniProtF8RL29|R1AB_AMV79 Replicase polyprotein 1ab (Gene Name=pp1ab)

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