Structure of PDB 5l8n Chain A

Receptor sequence
>5l8nA (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
FTGKFEMESEKNYDEFMKLLGISSDVIEKARNFKIVTEVQQDGQDFTWSQ
HYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEGGKLVVNFPNYHQTS
EIVGDKLVEVSTIGGVTYERVSKRL
3D structure
PDB5l8n Identification and Investigation of Novel Binding Fragments in the Fatty Acid Binding Protein 6 (FABP6).
ChainA
Resolution2.12 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6RQ A E12 Y15 A32 I37 E10 Y13 A30 I35 MOAD: Kd=31uM
PDBbind-CN: -logKd/Ki=4.51,Kd=31uM
BindingDB: Kd=2800nM
Gene Ontology
Molecular Function
GO:0005504 fatty acid binding
GO:0008289 lipid binding
Biological Process
GO:0006629 lipid metabolic process
GO:0006869 lipid transport
GO:0008285 negative regulation of cell population proliferation
GO:0015908 fatty acid transport
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:5l8n, PDBe:5l8n, PDBj:5l8n
PDBsum5l8n
PubMed27500412
UniProtP51161|FABP6_HUMAN Gastrotropin (Gene Name=FABP6)

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