Structure of PDB 5l87 Chain A

Receptor sequence
>5l87A (length=62) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
SEREKRVSNAVEFLLDSRVRRTPTSSKVHFLKSKGLSAEEICEAFTKVGQ
PKTLNEIKRILS
3D structure
PDB5l87 Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.
ChainA
Resolution0.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6RD A N13 E16 D20 R22 V23 F34 K38 N9 E12 D16 R18 V19 F30 K34 MOAD: Ki=8.43uM
PDBbind-CN: -logKd/Ki=5.07,Ki=8.43uM
Gene Ontology
Biological Process
GO:0016560 protein import into peroxisome matrix, docking
Cellular Component
GO:0005778 peroxisomal membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5l87, PDBe:5l87, PDBj:5l87
PDBsum5l87
PubMed28360328
UniProtQ8IEW2

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