Structure of PDB 5l0q Chain A

Receptor sequence
>5l0qA (length=203) Species: 9913 (Bos taurus) [Search protein sequence]
PVGLASGQPICGNGMVEQGEECDCGYSDQCKDECCYDANQPEGKKCKLKP
GKQCSPSQGPCCTAHCAFKSKTEKCRDDSDCAKEGICNGITALCPASDPK
PNFTDCNRHTQVCINGQCAGSICEKHGLEECTCASSDGKDDKELCHVCCM
KKMEPSTCASTGSVQWNKYFLGRTITLQPGSPCNDFRGYCDVFMRCRGSA
SGL
3D structure
PDB5l0q An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.
ChainA
Resolution2.759 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.81: ADAM10 endopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A I459 N462 M464 E466 E469 D472 I10 N13 M15 E17 E20 D23
External links
PDB RCSB:5l0q, PDBe:5l0q, PDBj:5l0q
PDBsum5l0q
PubMed27503072
UniProtQ10741|ADA10_BOVIN Disintegrin and metalloproteinase domain-containing protein 10 (Gene Name=ADAM10)

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