Structure of PDB 5l0h Chain A

Receptor sequence
>5l0hA (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
QPVNQPILAAAQSLHWEATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGS
GTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTI
STQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREA
EAASIKIRTDAGFTLRWVRKTPW
3D structure
PDB5l0h Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
ChainA
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PIO A W975 K979 K1103 R1107 R1128 W16 K20 K144 R148 R169 PDBbind-CN: -logKd/Ki=5.64,Kd=2.3uM
BS02 PO4 A S981 K983 S22 K24
BS03 PO4 A S981 S982 K983 K1129 S22 S23 K24 K170
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0051015 actin filament binding
Biological Process
GO:0007155 cell adhesion

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5l0h, PDBe:5l0h, PDBj:5l0h
PDBsum5l0h
PubMed27503891
UniProtP18206|VINC_HUMAN Vinculin (Gene Name=VCL)

[Back to BioLiP]