Structure of PDB 5ku1 Chain A

Receptor sequence
>5ku1A (length=398) Species: 9606 (Homo sapiens) [Search protein sequence]
MKPACIKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVK
NVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDL
DLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELK
DLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEY
LGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFRCNVIGVKNCG
KSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDISESE
AEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEV
KQEYSISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPHV
3D structure
PDB5ku1 Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
ChainA
Resolution2.501 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A N428 G430 K431 S432 L443 K447 K528 D530 L531 C559 N248 G250 K251 S252 L263 K267 K344 D346 L347 C375
BS02 MG A D197 D199 D201 T203 E208 D17 D19 D21 T23 E28
BS03 MG A D317 D319 D321 A323 E328 D137 D139 D141 A143 E148
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005509 calcium ion binding
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:5ku1, PDBe:5ku1, PDBj:5ku1
PDBsum5ku1
PubMed27605430
UniProtQ8IXI2|MIRO1_HUMAN Mitochondrial Rho GTPase 1 (Gene Name=RHOT1)

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