Structure of PDB 5ktl Chain A

Receptor sequence
>5ktlA (length=295) Species: 240292 (Trichormus variabilis ATCC 29413) [Search protein sequence]
SVGDFGTVLTAMITPFKADGSVNYAVAAELAAHLVDNGTDTLVVCGTTGE
SPTLSWDEEYNLFVEVLQTVAGKAKVIAGCGSNSTKEAIAATQKAAKIGV
HGTLQVVPYYNKPPQAGLYQHFQAIAQACPDLPLLLYNVPGRTGQNLSPE
TVVRLAEIDNIIGVKEASGNLDQAGEIRRSTPKEFQIYAGDDSLTLPLLA
IGAKGVVSVASHLVGNQLQQMIQAFNSGQVTVASDIHLRLLPLFKALFIT
TNPIPIKQALKLQGWEVGSTRPPLSDADAEVSQKLEAVMKHLNLI
3D structure
PDB5ktl Structure and Function of Cyanobacterial DHDPS and DHDPR.
ChainA
Resolution1.92 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T46 Y109 Y136 R141 K164 V206
Catalytic site (residue number reindexed from 1) T47 Y110 Y137 R142 K165 V207
Enzyme Commision number 4.3.3.7: 4-hydroxy-tetrahydrodipicolinate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A E64 Q67 E65 Q68
BS02 MN A S50 L53 E58 S51 L54 E59
Gene Ontology
Molecular Function
GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0009085 lysine biosynthetic process
GO:0009089 lysine biosynthetic process via diaminopimelate
GO:0019877 diaminopimelate biosynthetic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ktl, PDBe:5ktl, PDBj:5ktl
PDBsum5ktl
PubMed27845445
UniProtQ3M723

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