Structure of PDB 5krc Chain A

Receptor sequence
>5krcA (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]
NSLALSLTADQMVSALLDAEPPILYSEYDRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIR
HMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5krc Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 K362 L372 V376 E380 E542 I53 K57 L67 V71 E75 E227
BS02 ZER A L346 L349 A350 E353 L387 L391 M421 G521 L41 L44 A45 E48 L82 L86 M116 G206
External links
PDB RCSB:5krc, PDBe:5krc, PDBj:5krc
PDBsum5krc
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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