Structure of PDB 5kne Chain A

Receptor sequence
>5kneA (length=553) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
EYLSKYAIDMTEQARQGKLDPVIGREEEIRSTIRVLARRIKSNPCLIGEP
GIGKTAIIEGVAQRIIDDDVPTILQGAKLFSLDLAALTGDFEERFKGVLK
EIEESKTLIVLFIDEIHMLMGDAANILKPALSRGQLKVIGATTNNEYRSI
VEKDGAFERRFQKIEVAEPSVRQTVAILRGLQPKYEIHHGVRILDSALVT
AAQLAKRYLPYRRLPDSALDLVDISCAGVAVARDSSMIQNVVDSDTISET
AARLTGIPVKKLSESENEKLIHMERDLSSEVVGQMDAIKAVSNAVRLSRS
GLANPRQPASFLFLGLSGSGKTELAKKVAGFLFNDEDMMIRVDCSELSEK
YAVSKLLGTTYDEGGFLTNQLQYKPYSVLLFDEVEKAHPDVLTVMLQMLD
DGRITSGQGKTIDCSNCIVIMTSNLGAEFINSQQGSKIQESTKNLVMGAV
RQHFRPEFLNRISSIVIFNKLSRKAIHKIVDIRLKEIEERFEQNDKHYKL
NLTQEAKDFLAKYGYSDDMGARPLNRLIQNEILNKLALRILKNEIKDKET
VNV
3D structure
PDB5kne Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation.
ChainA
Resolution5.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A S616 G617 S618 G619 K620 T621 E622 S317 G318 S319 G320 K321 T322 E323
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0043531 ADP binding
GO:0051082 unfolded protein binding
GO:0051087 protein-folding chaperone binding
Biological Process
GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane
GO:0034605 cellular response to heat
GO:0034975 protein folding in endoplasmic reticulum
GO:0035617 stress granule disassembly
GO:0042026 protein refolding
GO:0043335 protein unfolding
GO:0051085 chaperone cofactor-dependent protein refolding
GO:0070370 cellular heat acclimation
GO:0070414 trehalose metabolism in response to heat stress
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0034399 nuclear periphery
GO:0072380 TRC complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5kne, PDBe:5kne, PDBj:5kne
PDBsum5kne
PubMed27478928
UniProtP31539|HS104_YEAST Heat shock protein 104 (Gene Name=HSP104)

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