Structure of PDB 5klb Chain A

Receptor sequence
>5klbA (length=267) Species: 367737 (Aliarcobacter butzleri RM4018) [Search protein sequence]
MYLRITNIVESSFFTKFIIYLIVLNGITMGLETSKTFMQSFGVYTTLFNQ
IVITIFTIEIILRIYVHRISFFKDPWSLFDFFVVAISLVPTSSGFEILRV
LRVLRLFRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQ
LFGERFPEWFGTLGESFYTLFQVMTLDDWSNGIVRPLMEVYPYAWVFFIP
FIFVVTFVMINLVVAIIVDAMAILNQKEEQHIIDEVQSHEDNINNEIIKL
REEIVELKELIKTSLKN
3D structure
PDB5klb Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A N1225 E1228 N225 E228
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0005261 monoatomic cation channel activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0001518 voltage-gated sodium channel complex
GO:0005886 plasma membrane
GO:0016020 membrane

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External links
PDB RCSB:5klb, PDBe:5klb, PDBj:5klb
PDBsum5klb
PubMed27556947
UniProtA8EVM5

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