Structure of PDB 5kl3 Chain A

Receptor sequence
>5kl3A (length=87) Species: 9606 (Homo sapiens) [Search protein sequence]
KPYQCDFKDCERRFSRSDHLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKT
HTRTHTGEKPFSCRWPSCQKKFARSDELVRHHNMHQR
3D structure
PDB5kl3 Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.
ChainA
Resolution1.449 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A F364 R366 H369 R372 H373 R376 S393 R394 H397 H401 T404 R424 R430 F14 R16 H19 R22 H23 R26 S43 R44 H47 H51 T54 R74 R80
BS02 dna A S395 D396 S425 S45 D46 S75
BS03 ZN A C355 C360 H373 H377 C5 C10 H23 H27
BS04 ZN A C385 C388 H401 H405 C35 C38 H51 H55
BS05 ZN A C413 C418 H431 H435 C63 C68 H81 H85
External links
PDB RCSB:5kl3, PDBe:5kl3, PDBj:5kl3
PDBsum5kl3
PubMed27596598
UniProtP19544|WT1_HUMAN Wilms tumor protein (Gene Name=WT1)

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