Structure of PDB 5kjy Chain A

Receptor sequence
>5kjyA (length=140) Species: 9606 (Homo sapiens) [Search protein sequence]
STLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGE
PGDEFFIILEGSAAVLQRRSEEFVEVRRLGPSDYFGEIALLMNRPRTATV
VARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSL
3D structure
PDB5kjy Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CMP A V302 Q304 R316 F324 G325 E326 I327 A328 R335 T336 Y373 N374 V65 Q67 R77 F85 G86 E87 I88 A89 R96 T97 Y134 N135
External links
PDB RCSB:5kjy, PDBe:5kjy, PDBj:5kjy
PDBsum5kjy
PubMed28583991
UniProtP10644|KAP0_HUMAN cAMP-dependent protein kinase type I-alpha regulatory subunit (Gene Name=PRKAR1A)

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