Structure of PDB 5kjx Chain A

Receptor sequence
>5kjxA (length=141) Species: 9606 (Homo sapiens) [Search protein sequence]
RKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGD
EFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVV
ARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV
3D structure
PDB5kjx Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CMP A V302 F324 G325 E326 I327 A328 R335 A336 Y373 N374 V62 F84 G85 E86 I87 A88 R95 A96 Y133 N134
External links
PDB RCSB:5kjx, PDBe:5kjx, PDBj:5kjx
PDBsum5kjx
PubMed28583991
UniProtP10644|KAP0_HUMAN cAMP-dependent protein kinase type I-alpha regulatory subunit (Gene Name=PRKAR1A)

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