Structure of PDB 5khd Chain A

Receptor sequence
>5khdA (length=72) Species: 953739 (Streptomyces venezuelae ATCC 10712) [Search protein sequence]
KLVLDLERLAHVPQEKAGPLQRYAATIQSQRGDYNGKVLSIRQDDLRTLA
VIYDQSPSVLTEQLISWGVLDA
3D structure
PDB5khd Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.
ChainA
Resolution1.7501 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C2E A Q113 R114 R125 D128 Q30 R31 R42 D45 MOAD: Kd=2.5uM
PDBbind-CN: -logKd/Ki=5.60,Kd=2.5uM
BS02 C2E A R114 G115 D116 R31 G32 D33 MOAD: Kd=2.5uM
PDBbind-CN: -logKd/Ki=5.60,Kd=2.5uM
BS03 C2E A K84 R114 S123 I124 R125 K1 R31 S40 I41 R42 MOAD: Kd=2.5uM
PDBbind-CN: -logKd/Ki=5.60,Kd=2.5uM
BS04 C2E A K84 D116 N118 V121 L122 S123 K1 D33 N35 V38 L39 S40 MOAD: Kd=2.5uM
PDBbind-CN: -logKd/Ki=5.60,Kd=2.5uM
Gene Ontology
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:5khd, PDBe:5khd, PDBj:5khd
PDBsum5khd
PubMed25171413
UniProtF2RCL8

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