Structure of PDB 5kej Chain A

Receptor sequence
>5kejA (length=222) Species: 29780 (Mangifera indica) [Search protein sequence]
AKSDVKLLGAWPSPYVMRARITLNVKSVDYELLEETLGSKSDLLLKSNPV
HKKIPVLIHNDKPICESLIIVHYIDEFWSSGPSILPSDPYDRAIARFWAA
YLDEKWYPSLKGIASAQGEEAKKAAVDQVGESLALIEDTYVKLSKGKPFF
GGEKIGYLDIAFGCFLGWLRVTEKTSGVKFLNEAKTPHLAKWAVRFCADP
AVKDVMPETEKLAEFAKLLAKF
3D structure
PDB5kej Insights into ligand binding to a glutathione S-transferase from mango: Structure, thermodynamics and kinetics.
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTX A S14 Y16 K54 I55 E67 S68 S13 Y15 K53 I54 E66 S67 MOAD: Kd=7.8uM
PDBbind-CN: -logKd/Ki=5.11,Kd=7.8uM
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
Biological Process
GO:0006749 glutathione metabolic process
GO:0009407 toxin catabolic process
GO:0009636 response to toxic substance
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:5kej, PDBe:5kej, PDBj:5kej
PDBsum5kej
PubMed28104507
UniProtA0A1P8NWC2

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