Structure of PDB 5keb Chain A

Receptor sequence
>5kebA (length=84) Species: 10090 (Mus musculus) [Search protein sequence]
HTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDDLTR
HYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
3D structure
PDB5keb Distinctive Klf4 mutants determine preference for DNA methylation status.
ChainA
Resolution2.453 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A Y411 K413 H416 R443 R449 K453 R471 H474 Y12 K14 H17 R44 R50 K54 R72 H75 PDBbind-CN: Kd=0.22uM
BS02 dna A K413 S415 Y430 K14 S16 Y31 PDBbind-CN: Kd=0.22uM
BS03 ZN A C462 C465 H478 H482 C63 C66 H79 H83
BS04 ZN A C432 C437 H450 H454 C33 C38 H51 H55
BS05 ZN A C402 C407 H420 H424 C3 C8 H21 H25
External links
PDB RCSB:5keb, PDBe:5keb, PDBj:5keb
PDBsum5keb
PubMed27596594
UniProtQ60793|KLF4_MOUSE Krueppel-like factor 4 (Gene Name=Klf4)

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