Structure of PDB 5ke9 Chain A

Receptor sequence
>5ke9A (length=88) Species: 10090 (Mus musculus) [Search protein sequence]
RTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSD
PLTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
3D structure
PDB5ke9 Distinctive Klf4 mutants determine preference for DNA methylation status.
ChainA
Resolution2.336 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A H416 W439 F441 R443 R449 H450 K453 R471 H474 H21 W44 F46 R48 R54 H55 K58 R76 H79 PDBbind-CN: Kd<3.6nM
BS02 dna A Y430 D445 F460 Y35 D50 F65 PDBbind-CN: Kd<3.6nM
BS03 ZN A C462 C465 H478 H482 C67 C70 H83 H87
BS04 ZN A C432 C437 H450 H454 C37 C42 H55 H59
BS05 ZN A C402 C407 H420 H424 C7 C12 H25 H29
External links
PDB RCSB:5ke9, PDBe:5ke9, PDBj:5ke9
PDBsum5ke9
PubMed27596594
UniProtQ60793|KLF4_MOUSE Krueppel-like factor 4 (Gene Name=Klf4)

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