Structure of PDB 5ke6 Chain A

Receptor sequence
>5ke6A (length=85) Species: 10090 (Mus musculus) [Search protein sequence]
THTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELT
RHYRKHTGHRPFQCQKCDRAFSRSDHLALHMKRHF
3D structure
PDB5ke6 Distinctive Klf4 mutants determine preference for DNA methylation status.
ChainA
Resolution1.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y411 H416 R443 E446 R449 R471 H474 Y13 H18 R45 E48 R51 R73 H76 PDBbind-CN: Kd=0.19uM
BS02 dna A K413 S415 Y430 D445 S472 K15 S17 Y32 D47 S74 PDBbind-CN: Kd=0.19uM
BS03 ZN A C462 C465 H478 H482 C64 C67 H80 H84
BS04 ZN A C432 C437 H450 H454 C34 C39 H52 H56
BS05 ZN A C402 C407 H420 H424 C4 C9 H22 H26
External links
PDB RCSB:5ke6, PDBe:5ke6, PDBj:5ke6
PDBsum5ke6
PubMed27596594
UniProtQ60793|KLF4_MOUSE Krueppel-like factor 4 (Gene Name=Klf4)

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