Structure of PDB 5kbd Chain A

Receptor sequence
>5kbdA (length=201) Species: 9606 (Homo sapiens) [Search protein sequence]
HEFIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPI
QIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPA
SHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSS
CVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYRE
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3D structure
PDB5kbd Structural Studies of Transcription Factor p73 DNA Binding Domain Bound to PA26 20-mer Response Element
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A S261 R268 R293 A296 C297 R300 S150 R157 R182 A185 C186 R189
BS02 ZN A C194 H197 C262 C83 H86 C151
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5kbd, PDBe:5kbd, PDBj:5kbd
PDBsum5kbd
PubMed
UniProtO15350|P73_HUMAN Tumor protein p73 (Gene Name=TP73)

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