Structure of PDB 5k8s Chain A

Receptor sequence
>5k8sA (length=146) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
GPGAKKRKMYEDILSHVNILKDMDPYERCKVADCLKSKSYNDGEIIIKEG
EEGDTFFILIDGNAVASKDNKVIKTYTKGDYFGELALLKNKPRAATIKAQ
NFCQVVYLDRKSFKRLLGPIEDILHRNVENYKKVLNELGLDTTCID
3D structure
PDB5k8s Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit.
ChainA
Resolution1.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.11: cAMP-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP A I340 I366 Y369 F375 G376 E377 L378 A379 R386 A387 A388 I390 Y424 L428 I47 I73 Y76 F82 G83 E84 L85 A86 R93 A94 A95 I97 Y131 L135 MOAD: Kd=6nM
PDBbind-CN: -logKd/Ki=8.22,Kd=6nM
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