Structure of PDB 5k8o Chain A

Receptor sequence
>5k8oA (length=422) Species: 376 (Bradyrhizobium sp.) [Search protein sequence]
SNDVAKVMKTLDGMREGLIQTAVELGSIEAPTGREGAAGDYVYEWMARNG
FGPERVGVFDDRFNVVGRLRGTGGGASLSFNSHLDTIMAREDTARFADAN
DRIYHEAWHEEGRIYGYSVVNCKGPMACWLIAAKALKEAGAALKGDVVLT
AVCGEIDCEPVDEFQGHDYLAEDIGARYAISHGAISDYALVAEATNFKPA
WVEAGKVFLKVTVFAGPSRYTPYVPRPVAALDSPNAIVRMAKLVEALEEW
ADNYEKRYTREYGGGTVVPKVAIGAIRGGVPYKIYRFPELCSIYMDIRLN
PDTNPLVVQREVEAVVSKLGLKAEVKPFLFRRGYEAQGIEPLQNALEVAH
REVVGRPTERPGSPECSMWRDTNPYNELGIPSLTYGCGGGAGGGNTYFLV
DDMLKAAKVYAMTAMDLCNRTP
3D structure
PDB5k8o Enzymatic hydrolysis by transition-metal-dependent nucleophilic aromatic substitution.
ChainA
Resolution2.893 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.99.8: 5-nitroanthranilic acid aminohydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H86 N124 E158 E196 H83 N121 E155 E193
BS02 6R7 A I90 N124 E158 E196 M371 R373 G395 I87 N121 E155 E193 M368 R370 G392 PDBbind-CN: -logKd/Ki=5.96,Kd=1.09uM
BS03 6R7 A Y223 Y288 R289 Y220 Y285 R286 PDBbind-CN: -logKd/Ki=5.96,Kd=1.09uM
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5k8o, PDBe:5k8o, PDBj:5k8o
PDBsum5k8o
PubMed27694799
UniProtD3WZ85|NAAA_BRASZ 5-nitroanthranilic acid aminohydrolase (Gene Name=naaA)

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