Structure of PDB 5k3e Chain A

Receptor sequence
>5k3eA (length=295) Species: 258594 (Rhodopseudomonas palustris CGA009) [Search protein sequence]
LADLFPGFGSEWINTSSGRIFARVGGDGPPLLLLHGFPQTHVMWHRVAPK
LAERFKVIVADLPGYGWSDMPESDEQHTPYTKRAMAKQLIEAMEQLGHVH
FALAGHNRGARVSYRLALDSPGRLSKLAVLDILPTYEYWQRMNRAYALKI
YHWSFLAQPAPLPENLLGGDPDFYVKAKLASWTRAGDLSAFDPRAVEHYR
IAFADPMRRHVMCEDYRAGAYADFEHDKIDVEAGNKIPVPMLALWGASGI
AQSTPLDVWRKWASDVQGAPIESGHFLPEEAPDQTAEALVRFFSA
3D structure
PDB5k3e The role of dimer asymmetry and protomer dynamics in enzyme catalysis.
ChainA
Resolution1.54 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F40 Q42 H109 N110 R111 D134 H155 Y219 G252 H280
Catalytic site (residue number reindexed from 1) F37 Q39 H106 N107 R108 D131 H152 Y216 G249 H275
Enzyme Commision number 3.8.1.3: haloacetate dehalogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GOA A N110 R111 R114 W156 Y219 H280 N107 R108 R111 W153 Y216 H275
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0018785 haloacetate dehalogenase activity

View graph for
Molecular Function
External links
PDB RCSB:5k3e, PDBe:5k3e, PDBj:5k3e
PDBsum5k3e
PubMed28104837
UniProtQ6NAM1|DEHA_RHOPA Fluoroacetate dehalogenase (Gene Name=RPA1163)

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