Structure of PDB 5k3b Chain A

Receptor sequence
>5k3bA (length=295) Species: 258594 (Rhodopseudomonas palustris CGA009) [Search protein sequence]
DLADLFPGFGSEWINTSSGRIFARVGGDGPPLLLLHGFPQTHVMWHRVAP
KLAERFKVIVADLPGYGWSDMPESDEQHTPYTKRAMAKQLIEAMEQLGHV
HFALAGHNRGARVSYRLALDSPGRLSKLAVLDILPTYEYWQRMNRAYALK
IYHWSFLAQPAPLPENLLGGDPDFYVKAKLASWTRAGDLSAFDPRAVEHY
RIAFADPMRRHVMCEDYRAGAYADFEHDKIDVEAGNKIPVPMLALWGASG
IAQTPLDVWRKWASDVQGAPIESGHFLPEEAPDQTAEALVRFFSA
3D structure
PDB5k3b The role of dimer asymmetry and protomer dynamics in enzyme catalysis.
ChainA
Resolution1.58 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F40 Q42 H109 N110 R111 D134 H155 Y219 G252 H280
Catalytic site (residue number reindexed from 1) F38 Q40 H107 N108 R109 D132 H153 Y217 G250 H275
Enzyme Commision number 3.8.1.3: haloacetate dehalogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 R3W A N110 R111 R114 H155 W185 Y219 N108 R109 R112 H153 W183 Y217
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0018785 haloacetate dehalogenase activity

View graph for
Molecular Function
External links
PDB RCSB:5k3b, PDBe:5k3b, PDBj:5k3b
PDBsum5k3b
PubMed28104837
UniProtQ6NAM1|DEHA_RHOPA Fluoroacetate dehalogenase (Gene Name=RPA1163)

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