Structure of PDB 5k30 Chain A

Receptor sequence
>5k30A (length=386) Species: 546 (Citrobacter freundii) [Search protein sequence]
SDCRTYGFNTQIVHAGQQPDPSTGALSTPIFQTSTFVFDSAEQGAARFRL
GNPTTDALEKKLAVLERGEAGLATASGISAITTTLLTLCQQGDHIVSASA
IYGCTHAFLSHSMPKFGINVSFVDAAKPEEIRAAMRPETKVVYIETPANP
TLSLVDIETVAGIAHQQGALLVVDNTFMSPYCQQPLQLGADIVVHSVTKY
INGHGDVIGGIIVGKQEFIDQARFVGLKDITGGCMSPFNAWLTLRGVKTL
GIRMERHCENALKIARFLEGHPSITRVYYPGLSSHPQYELGQRQMSLPGG
IISFEIAGGLEAGRRMINSVELCLLAVSLGDTETLIQHPASMTHSPVAPE
ERLKAGITDGLIRLSVGLEDPEDIINDLEHAIRKAT
3D structure
PDB5k30 Sulfoxides of sulfur-containing amino acids are suicide substrates of Citrobacter freundii methionine gamma-lyase. Structural bases of the enzyme inactivation.
ChainA
Resolution1.59 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R60 Y113 D185 K210
Catalytic site (residue number reindexed from 1) R49 Y102 D174 K199
Enzyme Commision number 4.4.1.11: methionine gamma-lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A G88 I89 Y113 E156 D185 T187 F188 S207 T209 K210 G77 I78 Y102 E145 D174 T176 F177 S196 T198 K199
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0016846 carbon-sulfur lyase activity
GO:0018826 methionine gamma-lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0019346 transsulfuration
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5k30, PDBe:5k30, PDBj:5k30
PDBsum5k30
PubMed31711941
UniProtA0A0A5P8W7

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