Structure of PDB 5k2c Chain A

Receptor sequence
>5k2cA (length=396) Species: 562,9606 [Search protein sequence]
DGAPPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVS
LAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLA
IAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCG
QPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVY
LRIFLAARRQLADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALD
AQKATPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNA
YIQKYLERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDC
SHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVL
3D structure
PDB5k2c Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZMA A L85 F168 E169 M177 L249 H250 N253 M270 L88 F171 E172 M180 L337 H338 N341 M358
BS02 CLR A A72 G76 A75 G79
BS03 CLR A P248 F255 S263 P336 F343 S351
Gene Ontology
Molecular Function
GO:0001609 G protein-coupled adenosine receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0001973 G protein-coupled adenosine receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:5k2c, PDBe:5k2c, PDBj:5k2c
PDBsum5k2c
PubMed27679816
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P29274|AA2AR_HUMAN Adenosine receptor A2a (Gene Name=ADORA2A)

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