Structure of PDB 5jzd Chain A

Receptor sequence
>5jzdA (length=378) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
ATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFAD
AKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQ
SLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAID
SGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLA
GSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVP
SSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAAT
QVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAG
IVPASSPLGEWRETGVKLSTMLNVFGLH
3D structure
PDB5jzd An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.
ChainA
Resolution2.303 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K147 E197 A213 E241 H276 A303 F327 R347 G363 E376 K380
Catalytic site (residue number reindexed from 1) K134 E184 A200 E228 H263 A290 F314 R334 G350 E363 K367
Enzyme Commision number 5.4.4.2: isochorismate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ISC A G214 S215 E241 H276 A303 I346 R347 A360 G361 E376 K380 G201 S202 E228 H263 A290 I333 R334 A347 G348 E363 K367
BS02 MG A E241 E376 E228 E363
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0008909 isochorismate synthase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0009058 biosynthetic process
GO:0009239 enterobactin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5jzd, PDBe:5jzd, PDBj:5jzd
PDBsum5jzd
PubMed27373320
UniProtP0AEJ2|ENTC_ECOLI Isochorismate synthase EntC (Gene Name=entC)

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