Structure of PDB 5jur Chain A

Receptor sequence
>5jurA (length=150) Species: 383596 (Influenza A virus (A/Beijing/39/1975(H3N2))) [Search protein sequence]
SSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRA
TAILRKATRRLVQLIVSGKDEQSIAEAIIVAMVFSQEDCMIKAVRNPMHQ
LLRHFQKDAKVLFQNWGIEHIDNVMGMVGVLPDMTPSTEMSMRGIRVSKM
3D structure
PDB5jur Discovery of Novel, Orally Bioavailable beta-Amino Acid Azaindole Inhibitors of Influenza PB2.
ChainA
Resolution2.93 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 6NS A F23 F25 H57 E61 F63 K76 F104 Q106 M131 F3 F5 H37 E41 F43 K56 F84 Q86 M98 PDBbind-CN: -logKd/Ki=8.52,Kd=0.003uM
External links
PDB RCSB:5jur, PDBe:5jur, PDBj:5jur
PDBsum5jur
PubMed28197322
UniProtQ30NP1|PB2_I75A0 Polymerase basic protein 2 (Gene Name=PB2)

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