Structure of PDB 5jug Chain A

Receptor sequence

>5jugA (length=168) Species: 1415550 (Streptomyces sp. NRRL B-16215)

SACPSGATCGSYTVGGLGSRKQQVRNAGGSSLDLAVAMLQTERMDTAYPY
GDNKSGDAANFGIFKQNWLMLRSACAQFGGQGAGQYDNGAALNSSLGQDV
SCLHQSQSHYGLDAWFAGHRNGASGLSSPNTADIAAYKAAVYWIKAQLDA
DSANLGNDTRFWVQVPAI

3D structure

• PDB: 5jug A beta-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism.
• Chain: A
• Resolution: 0.96 Å

Enzymatic activity

• Enzyme Commision number: 3.2.1.78: mannan endo-1,4-beta-mannosidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	BMA	A	L44 R165 W167 V168 Q169 V170	L39 R160 W162 V163 Q164 V165
BS02	BMA	A	Q45 K70 R125 V170 P171	Q40 K65 R120 V165 P166
BS03	BMA	A	Q45 N65 H124 R125 Y142 A172 I173	Q40 N60 H119 R120 Y137 A167 I168
BS04	BMA	A	K59 A63 N65 N72 R125 N126 G127 I173	K54 A58 N60 N67 R120 N121 G122 I168
BS05	BMA	A	D62 A63 N126 G127 A128 S129	D57 A58 N121 G122 A123 S124
BS06	MAN	A	L44 R165 V168 Q169 V170	L39 R160 V163 Q164 V165

Gene Ontology

Molecular Function

• GO:0016985 mannan endo-1,4-beta-mannosidase activity

External links

• PDB: RCSB:5jug, PDBe:5jug, PDBj:5jug
• PDBsum: 5jug
• PubMed: 28058278
• UniProt: A0A1L1QK16