Structure of PDB 5jsj Chain A

Receptor sequence
>5jsjA (length=195) Species: 9606 (Homo sapiens) [Search protein sequence]
SRRNIVGCRIQHGWKEGNGPVTQWKGTVLDQVPVNPSLYLIKYDGFDCVY
GLELNKDERVSALEVLPDRVATSRISDAHLADTMIGKAVEHMFETEDGSK
DEWRGMVLARAPVMNTWFYITYEKDPVLYMYQLLDDYKEGDLRIMPDSLV
GKQVEYAKEDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLV
3D structure
PDB5jsj Developing Spindlin1 small-molecule inhibitors by using protein microarrays
ChainA
Resolution2.348 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6PD A W62 W72 Y91 F94 C96 Y98 F141 W151 D173 Y177 Y179 H252 W14 W24 Y43 F46 C48 Y50 F93 W103 D125 Y129 Y131 H188 MOAD: Kd=4uM
PDBbind-CN: -logKd/Ki=5.40,Kd=4uM
BindingDB: Kd=4000nM
Gene Ontology
Biological Process
GO:0007276 gamete generation

View graph for
Biological Process
External links
PDB RCSB:5jsj, PDBe:5jsj, PDBj:5jsj
PDBsum5jsj
PubMed28504676
UniProtQ9Y657|SPIN1_HUMAN Spindlin-1 (Gene Name=SPIN1)

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