Structure of PDB 5jq7 Chain A

Receptor sequence
>5jq7A (length=257) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search protein sequence]
GRSIPLGVIHNSALQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDV
PSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGI
RGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEG
VVAFLILPQAKSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFT
PQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTEWAFWETSEELSFTVV
AAAAAAA
3D structure
PDB5jq7 Toremifene interacts with and destabilizes the Ebola virus glycoprotein.
ChainA
Resolution2.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 T0R A R64 V66 E100 A101 L186 R35 V37 E71 A72 L157 PDBbind-CN: -logKd/Ki=4.80,Kd=16uM
BindingDB: EC50=63nM,Kd=16000nM
External links
PDB RCSB:5jq7, PDBe:5jq7, PDBj:5jq7
PDBsum5jq7
PubMed27362232
UniProtQ05320|VGP_EBOZM Envelope glycoprotein (Gene Name=GP)

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