Structure of PDB 5jpg Chain A

Receptor sequence
>5jpgA (length=144) Species: 10116 (Rattus norvegicus) [Search protein sequence]
SSFSTQTPYPNLAVPFFTSIPNGLYPSKSIVISGVVLSDAKRFQINLRCG
GDIAFHLNPRFDENAVVRNTQINNSWGPEERSLPGSMPFSRGQRFSVWIL
CEGHCFKVAVDGQHICEYSHRLMNLPDINTLEVAGDIQLTHVET
3D structure
PDB5jpg Structural Characterization of Rat Galectin-5, an N-Tailed Monomeric Proto-Type-like Galectin.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC A R61 E80 R60 E79
BS02 GAL A H57 R61 N70 W77 E80 H56 R60 N69 W76 E79
Gene Ontology
Molecular Function
GO:0016936 galactoside binding
GO:0030246 carbohydrate binding
GO:0030395 lactose binding
Biological Process
GO:0010628 positive regulation of gene expression
GO:0032689 negative regulation of type II interferon production
GO:0070234 positive regulation of T cell apoptotic process
GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5jpg, PDBe:5jpg, PDBj:5jpg
PDBsum5jpg
PubMed34944498
UniProtP47967|LEG5_RAT Galectin-5 (Gene Name=Lgals5)

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