Structure of PDB 5jox Chain A

Receptor sequence

>5joxA (length=502) Species: 28116 (Bacteroides ovatus)

HQGYSNPVIPGFHPDPSVCKAGDDYYLVNSSFQYFPGVPLFHSKDLVHWE
QIGNCLTRPSQLDLTNANSGSGIFAPTIRYNDGVFYMITTNVSGKGNFLV
HTTDPRSEWSEPVWLEQGGIDPSLYFEDGKCFMVSNPDGYINLCEIDPMT
GKQLSSSKRIWNGTGGRYAEGPHIYKKDGWYYLLISEGGTELGHKVTIAR
SRYIDGPYQGNPANPILTHANESGQSSPIQGTGHADLVEGTDGSWWMVCL
AYRIMPGTHHTLGRETYLAPVRWDKDAWPVVNSNGTISLKMDVPTLPQQE
MKGRPERIDFKEGKLSPEWIHLQNPEAKNYIFTKDGKLRLIATPVTLSDW
KSPTFVALRQEHFDMEASAPVVLQKAGVNDEAGISVFMEFHSHYDLFVRQ
DKDRKRSVGLRYKLGEITHYAKEVSLPTDGEVELVVKSDINYYYFGYKVN
GIYHDLGKMNTRYLSTETAGGFTGVVLGLYITSASKDSKAYADFEYFKYK
GK

3D structure

• PDB: 5jox Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut.
• Chain: A
• Resolution: 1.8 Å

Enzymatic activity

• Enzyme Commision number: 3.2.1.55: non-reducing end alpha-L-arabinofuranosidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	EDG	A	D34 F51 A94 D140 E189 H253 R283	D15 F32 A75 D121 E170 H234 R264	MOAD: Kd=35uM PDBbind-CN: -logKd/Ki=4.46,Kd=35uM

Gene Ontology

Molecular Function

• GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0046556 alpha-L-arabinofuranosidase activity

Biological Process

• GO:0000272 polysaccharide catabolic process
• GO:0005975 carbohydrate metabolic process
• GO:0085030 symbiotic process benefiting host
• GO:2000899 xyloglucan catabolic process

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:5jox, PDBe:5jox, PDBj:5jox
• PDBsum: 5jox
• PubMed: 27466444
• UniProt: A7LXT8|GH43A_BACO1 Non-reducing end alpha-L-arabinofuranosidase BoGH43A (Gene Name=BACOVA_02654)