Structure of PDB 5jjv Chain A

Receptor sequence

>5jjvA (length=353) Species: 85962 (Helicobacter pylori 26695)

MKHPLEELKDPTENLLLWIGRFLRYKCTSLSNSQVKDQNKVFECLNELNQ
ACSSSQLEKVCKKARNAGLLGINTYALPLLKFHEYFSKAFNSLKNIDEVM
LAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLK
NISGVNQSAGNKLPTHLNNEELEKFLESIDKIEMSAKVRARNRLLIKIIV
FTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAVMLKAFHIESLLK
EWLIERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGA
HMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASI
WEE

3D structure

• PDB: 5jjv Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending.
• Chain: A
• Resolution: 2.4 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	K62 R65 N66 L77 S121 A123 T124 N127 K170 S193 V196 R199 N277 Q278 L283 T284 A286 Y287 K290 K305 H309 R312 H313 T340	K62 R65 N66 L77 S113 A115 T116 N119 K162 S185 V188 R191 N269 Q270 L275 T276 A278 Y279 K282 K297 H301 R304 H305 T332
BS02	dna	A	K26 L30 S31 L70 G71 T74 Y75 R129 I130 R213 S214 N215 Q285 Y289 K305 G307 H309	K26 L30 S31 L70 G71 T74 Y75 R121 I122 R205 S206 N207 Q277 Y281 K297 G299 H301

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0009037 tyrosine-based site-specific recombinase activity

Biological Process

• GO:0006310 DNA recombination
• GO:0007059 chromosome segregation
• GO:0015074 DNA integration
• GO:0051301 cell division

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:5jjv, PDBe:5jjv, PDBj:5jjv
• PDBsum: 5jjv
• PubMed: 28009253
• UniProt: O25386|XERH_HELPY Tyrosine recombinase XerH (Gene Name=xerH)