Structure of PDB 5jju Chain A

Receptor sequence
>5jjuA (length=325) Species: 419947 (Mycobacterium tuberculosis H37Ra) [Search protein sequence]
GARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLDGCGKRVE
VSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALG
DLTDSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPID
PRVAHCIYAGLATDTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSH
PFTWLPLLSRVLGSAQLVSEAVGGRGLVYVVVDNREWVAARSEEVESIVD
IVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNLAAVASGFGGGGHRLAAG
YTTTGSIDDAVASLRAALGLTRAPP
3D structure
PDB5jju Structural and biochemical insight into the mechanism of Rv2837c from Mycobacterium tuberculosis as a c-di-NMP phosphodiesterase
ChainA
Resolution2.312 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A D45 R112 H132 D181 W187 S292 R294 G309 G310 G311 H312 A315 G317 Y318 D28 R95 H115 D164 W170 S275 R277 G292 G293 G294 H295 A298 G300 Y301
BS02 MN A D47 D106 H131 D181 D30 D89 H114 D164
BS03 MN A H41 D45 D106 H24 D28 D89
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5jju, PDBe:5jju, PDBj:5jju
PDBsum5jju
PubMed27371563
UniProtA5U6I9

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