Structure of PDB 5jhk Chain A

Receptor sequence
>5jhkA (length=154) Species: 9606 (Homo sapiens) [Search protein sequence]
KCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYR
EWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIK
EGNKPVLFQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYG
CKIT
3D structure
PDB5jhk Architecture and hydration of the arginine-binding site of neuropilin-1.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6K8 A Y297 W301 T316 D320 S346 T349 Y353 G414 I415 Y24 W28 T43 D47 S73 T76 Y80 G141 I142 PDBbind-CN: -logKd/Ki=4.64,Kd=23uM
External links
PDB RCSB:5jhk, PDBe:5jhk, PDBj:5jhk
PDBsum5jhk
PubMed29430837
UniProtO14786|NRP1_HUMAN Neuropilin-1 (Gene Name=NRP1)

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