Structure of PDB 5jh2 Chain A

Receptor sequence
>5jh2A (length=257) Species: 4577 (Zea mays) [Search protein sequence]
ARHFVLNTGAKIPSVGLGSWQSDPGVVGNAVYAAVKAGYRHIDCARVYGN
EKEIGLALKKLFEEGVVKREDMFITSKLWNDHHAPEDVPEALNDSLNDLQ
LEYLDLYLIHWPFFPATWGAMEKLYDAGKARAIGVSNFSSKKLGDLLAVA
RVPPAVDQVECHPGWQQTKLHSFCQSTGVHLTAYSPLGNVLKEPIIISIA
EKLGKTSAQVALRWNIQMGHSVLPKSTNEERIKQNLDVYDWSIPDDLLAK
FSEIKQA
3D structure
PDB5jh2 A comparative structural analysis reveals distinctive features of co-factor binding and substrate specificity in plant aldo-keto reductases.
ChainA
Resolution1.72 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D44 Y49 K78 H111
Catalytic site (residue number reindexed from 1) D43 Y48 K77 H110
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A2P A S203 P204 L205 G206 A235 K252 S253 T254 R258 N262 S185 P186 L187 G188 A208 K225 S226 T227 R231 N235
Gene Ontology
Molecular Function
GO:0004032 aldose reductase (NADPH) activity
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:5jh2, PDBe:5jh2, PDBj:5jh2
PDBsum5jh2
PubMed27154221
UniProtA2T1W7

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