Structure of PDB 5je8 Chain A

Receptor sequence
>5je8A (length=291) Species: 226900 (Bacillus cereus ATCC 14579) [Search protein sequence]
MKKIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKEGGIIGLS
ISKLAETCDVVFTSLPSPRAVEAVYFGAEGLFENGHSNVVFIDTSTVSPQ
LNKQLEEAAKEKKVDFLAAPVSGGVIGAENRTLTFMVGGSKDVYEKTESI
MGVLGANIFHVSEQIDSGTTVKLINNLLIGFYTAGVSEALTLAKKNNMDL
DKMFDILNVSYGQSRIYERNYKSFIAPENYEPGFTVNLLKKDLGFAVDLA
KESELHLPVSEMLLNVYDEASQAGYGENDMAALYKKVSEQL
3D structure
PDB5je8 Structural and biochemical characterization of the Bacillus cereus 3-hydroxyisobutyrate dehydrogenase
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.31: 3-hydroxyisobutyrate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G10 N11 M12 D31 L32 L65 P66 V74 S95 T96 V121 L238 G10 N11 M12 D31 L32 L65 P66 V74 S95 T96 V121 L238
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008442 3-hydroxyisobutyrate dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding
Biological Process
GO:0016054 organic acid catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5je8, PDBe:5je8, PDBj:5je8
PDBsum5je8
PubMed27120461
UniProtQ81DR6

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