Structure of PDB 5jbx Chain A

Receptor sequence
>5jbxA (length=258) Species: 246197 (Myxococcus xanthus DK 1622) [Search protein sequence]
MPEFKVDARGPIEIWTIDGESRRNAISRAMLKELGELVTRVSSSRDVRAV
VITGAGDKAFCAGADLKERATMAEDEVRAFLDGLRRTFRAIEKSDCVFIA
AINGAALGGGTELALACDLRVAAPAAELGLTEVKLGIIPGGGGTQRLARL
VGPGRAKDLILTARRINAAEAFSVGLANRLAPEGHLLAVAYGLAESVVEN
APIAVATAKHAIDEGTGLELDDALALELRKYEEILKTEDRLEGLRAFAEK
RAPVYKGR
3D structure
PDB5jbx The Structure of LiuC, a 3-Hydroxy-3-Methylglutaconyl CoA Dehydratase Involved in Isovaleryl-CoA Biosynthesis in Myxococcus xanthus, Reveals Insights into Specificity and Catalysis.
ChainA
Resolution1.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) A64 R69 L81 R85 G109 E112 T131 E132 I137 P139 G140 A225 L235
Catalytic site (residue number reindexed from 1) A64 R69 L81 R85 G109 E112 T131 E132 I137 P139 G140 A225 L235
Enzyme Commision number 4.2.1.55: 3-hydroxybutyryl-CoA dehydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A S21 R22 R23 A62 A64 D65 L66 L107 G108 T131 E132 L135 S21 R22 R23 A62 A64 D65 L66 L107 G108 T131 E132 L135
BS02 COA A F247 K250 F247 K250
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016836 hydro-lyase activity
Biological Process
GO:0006635 fatty acid beta-oxidation

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Molecular Function
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Biological Process
External links
PDB RCSB:5jbx, PDBe:5jbx, PDBj:5jbx
PDBsum5jbx
PubMed27271456
UniProtQ1D5Y4

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