Structure of PDB 5j8c Chain A

Receptor sequence
>5j8cA (length=272) Species: 9606 (Homo sapiens) [Search protein sequence]
GSKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYR
FHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHK
TLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVASILTLPPYQ
RRGYGKFLIAFSYELSKLESTVGSPQKPLSDLGKLSYRSYWSWVLLEILR
DFGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEH
LKSAQYKKPPITVDSVCLKWAP
3D structure
PDB5j8c Structural and Functional Role of Acetyltransferase hMOF K274 Autoacetylation.
ChainA
Resolution2.17 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S316 Q350
Catalytic site (residue number reindexed from 1) S142 Q176
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C210 C213 H226 C230 C36 C39 H52 C56
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5j8c, PDBe:5j8c, PDBj:5j8c
PDBsum5j8c
PubMed27382063
UniProtQ9H7Z6|KAT8_HUMAN Histone acetyltransferase KAT8 (Gene Name=KAT8)

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